In Respect for Nature Paul W. Taylor argues that there is a moral obligation to respect all living things. I argue that there is no such obligation. Taylor presents three basic premises for his position. The first two are shown to be mistaken but not necessary for Taylor's argument. The third, that being a nonsentient teleological centre of life confers moral significance, while necessary, fails to be rationally compelling. I argue: (1) The relevant concept of teleology as readily applies to (...) inanimate objects as it does to nonsentient life forms. (2) The inanimate–nonsentient distinction (at the relevant molecular level) is founded upon a continuum which offes no basis sufficient to justify The Life Principle. (3) The concept of teleology, as used by Taylor, is too unclear and ill-founded to serve as the basis for a rationally compelling argument. (shrink)

Drug Safety Communications are used by the Food and Drug Administration to inform health care providers, patients, caregivers, and the general public about safety issues related to FDA-approved drugs. To assess patient knowledge of the messaging contained in DSCs related to the sleep aids zolpidem and eszopiclone, we conducted a large, cross-sectional patient survey of 1,982 commercially insured patients selected by stratified random sampling from the Optum Research Database who had filled at least two prescriptions for either zolpidem or eszopiclone (...) between July 1, 2012 and June 30, 2013. Among the 594 respondents, two-thirds reported hearing generally about drug safety information prior to starting a new drug, with the remaining one-third “rarely” or “never” hearing such information. Providers and pharmacists were primary sources of drug safety information. Two-thirds of zolpidem users and half of eszopiclone users reported having heard about the related DSC messages, ability to accurately identify the major factual messages was limited. Respondents reacted to new drug safety information about their sleep aids by reporting that they would want to learn about alternative ways to help them sleep and seek out more information about the safety of their specific sleeping pill. Opportunities may exist for the FDA to work with providers and pharmacies to help ensure the DSC information is more widely received and is more fully understood by those taking the affected medications. (shrink)

Mortal and immortal DNA : Craig Venter and the lure of "lamia" -- Homeopathy : Holmes, hogwarts, and the Prince of Wales -- Citizen Pinel and the madman at Bellevue -- The experimental pathology of stress : Hans Selye to Paris Hilton -- Gore's fever and Dante's Inferno : Chikungunya reaches Ravenna -- Giving things their proper names : Carl Linnaeus and W.H. Auden -- Spinal irritation and fibromyalgia : Lincoln's surgeon general and the three graces -- Tithonus and the (...) fruit fly : new science and old myths -- Swiftboating "America the beautiful" : Katharine Lee Bates and a Boston marriage -- Nothing makes sense in medicine except in the light of biology -- Apply directly to the forehead : Holmes, Zola, and Hennapecia -- Elizabeth Blackwell breaks the bonds -- Chronic lyme disease and medically unexplained syndromes -- Eugenics and the immigrant : Rosalyn Yalow and Rita Levi-Montalcini -- Science in the Middle East : Robert Koch and the cholera war -- How to win a Nobel prize : thinking inside and outside the box -- Homer Smith and the lungfish : the last gasp of intelligent design -- DDT is back : let us spray! -- Academic boycotts and the Royal Society -- Teach evolution, learn science : John William Draper and the "bone bill" -- Diderot and the yeti crab : the encyclopedias of life -- Dengue fever in Rio : Macumba versus Voltaire. (shrink)

This volume is a “state-of-the-art‘ assessment of comparative philosophy written by some of the leading practitioners of the field. While its primary focus is on gaining methodological clarity regarding the comparative enterprise of “interpreting across boundaries,‘ the book also contains new substantive essays on Indian, Chinese, Japanese, and European thought. The contributors are Roger T. Ames, William Theodore de Bary, Wing-tsit Chan, A. S. Cua, Eliot Deutsch, Charles Hartshorne, Daya Krishna, Gerald James Larson, Sengaku Mayeda, Hajime Nakamura, Raimundo Panikkar, (...) Karl H. Potter, Henry Rosemont, Jr., Ben-Ami Scharfstein, Ninian Smart, Fritz Staal, and Frederick J. Streng. Comparative or cross-cultural philosophy can be seen as a relative newcomer to the field of philosophy. It has its antecedents in the emergence of comparative studies in nineteenth-century European intellectual history, as well as in the sequence of East-West Philosophers’ Conferences at the University of Hawaii, which began in 1939. This book will prove to be of great significance in helping to define a field that is only now becoming fully self-conscious, methodologically and substantively, about its role and function in the larger enterprises of philosophy and comparative studies. (shrink)

Nowhere has H.L.A. Hart's influence on philosophical jurisprudence in the English-speaking world been greater than in the way its fundamental project and method are conceived by its practitioners. Disagreements abound, of course. Philosophers debate the extent to which jurisprudence can or should proceed without appeal to moral or other values. They disagree about which participant perspective—that of the judge, lawyer, citizen, or “bad man”—is primary and about what taking up the participant perspective commits the theorist to. However, virtually unchallenged is (...) the view that jurisprudence is fundamentally interpretive or “hermeneutic”; that it takes for its subject a certain kind of social practice, constituted by the behavior and understandings of its participants; that its task is to explain this practice and its relations to other important social practices; and that it can properly be explained only by taking full account of participant understandings. It is, perhaps, some measure of the hegemony of Hart's influence that Ronald Dworkin mounts his fundamental challenge to Hart's positivism squarely from within this jurisprudential orthodoxy. Dworkin may have exceeded the limits of the method as Hart conceived it, but, as Stephen Perry has argued, “the seeds of Dworkin's strong version of inter-pretivism were sown by Hart himself.”. (shrink)

In lieu of an abstract, here is a brief excerpt of the content:Journal of the History of Philosophy 40.4 (2002) 415 [Access article in PDF] Editor's Note THIS ISSUE MARKS THE COMPLETION of the Journal's fortieth year of publication. In recognition of that milestone we include a few special items. First is a birthday message from the Journal's Founding Editor, Richard H. Popkin. Then, in the Notes and Discussions, we carry on our tradition of occasional debates about what we do (...) and why it is important, with remarks by Richard A. Watson and Margaret J. Osler. For earlier discussions, see 2 (1961), 1-14 and 31 (1993), 95-123. Gerald A. Press... (shrink)

First published in 1983. The primary argument of this book is that there is a coherent tradition of liberal thinking that extends from L. S. Mill, through liberals like T. H. Green, Bernard Bosanquet, L. T. Hobhouse and John Dewey to John Rawls. The author places Rawls within a longstanding tradition of liberal thinking, while also arguing that Green and Hobhouse are not simply of historical interest but represent genuine and interesting attempts to develop a modern liberal theory. It is (...) argued that modern liberal theory centres on a conception of human nature; that modern liberals have sought to harmonise the pursuit of individuality with participation in social and communal life. Although the book focuses on six modern liberals, the discussion proceeds topically rather than according to author, thus highlighting similarities and disagreements and providing a comprehensive study of modern liberalism. (shrink)

In his Lectures on the Principles of Political Obligation, T. H. Green characterizes a right as ‘a power claimed and recognized as contributory to a common good’ (LPPO §99). Scholars such as Rex Martin have noted that Green’s characterization of a right has multiple elements: it includes social recognition and the common good,1 as well as the idea of a power. More formally, it seems that Green wants to say that R is a right if and only if R is (...) (i) a power that is (ii) recognized by some others or by society as (iii) contributing to a common good. Much of the scholarship on Green has been devoted to explicating and defending this third feature, which grounds rights on Green’s core idea of a common good.2 In this chapter I shall stress claim (ii) —the recognition thesis —though we shall see that pursuing claim (ii) will enlighten us as to why Green links the recognition thesis to the common good claim, (iii). And claim (i), I shall argue, reinforces the plausibility of the recognition thesis. So.. (shrink)

In lieu of an abstract, here is a brief excerpt of the content:Reviewed by:The Database of Classical Bibliography ed. by Dee. L. ClaymanGerald A. PressDee. L. Clayman, editor. The Database of Classical Bibliography. CD-ROM and manual. Atlanta: Scholars Press, 1997. Pp. xvi + 120. $85 (individual); $340-2400 (institutional).L ’Annee Philologique (APh) has long been one of the most important scholarly resources for students of the history of ancient philosophy. Even though in print form it contains errors and omissions, has become (...) of unwieldy size, and does not appear promptly enough for up-to-date research, there is no other single source of such international comprehensiveness. It is far more inclusive in many respects than The Philosopher’s Index.The Database of Classical Bibliography (DCB) is a long-term project sponsored by the N.E.H., the American Philological Association and others to make the full contents of APh accessible from a CD-ROM either from individual PCs or on a local network. Unlike the Thesaurus Linguae Graecae, the DCB CD-ROM comes with its own search software (DCB CompLex) on the disk. This software is set up both for IBM and MAC machines, installs quickly, and operates extremely well. The manual gives clear instructions both for general use and for detailed search strategies. CompLex enables the user to search DCD in many different ways; e.g., by ancient or modern authors and works, by titles, publisher, place of publication, year of publication, journal, modern language, or series name, as well as by APh volumes, years, page numbers, rubrics, and topics. It can also search by any word in a modern language (i.e., in Roman characters) or for words in a Greek index. And CompLex enables one to perform more complex searches utilizing wildcards and Boolean operators in a user-friendly form.DCB Version 2, containing Volumes 45–60 (1974–1989), fulfills the editor’s initial commitment to make a new release available each year with the addition of three to five years, since it includes four years of APh (1973–74 and 1988–89) not on Version 1. Also new in Version 2 is a French interface and manual.DCB has faults, however. It repeats mistakes that appeared in the print version of APh and contains other mistakes that did not originate in APh. Many were noted in reviews of Version 1, but this should not be surprising in a work of such magnitude as either APh or DCB. What is perhaps disturbing is that errors noted in Version 1 have not been corrected in Version 2, though it would not seem difficult to make use of the information provided by careful reviewers.Nevertheless, DCB is a terrific scholarly tool. No college or university library should be without it. [End Page 619]Gerald A. PressHunter CollegeCopyright © 1998 Journal of the History of Philosophy, Inc... (shrink)

Establishing acceptable norms of behavior and consistent standards of conduct has been part of the human enterprise since the dawn of time. Without principles of ethics and the moral rules that affect individual behavior, humankind would plunge into a state of chaotic indifference, insecurity, and unending fear. But while few question the need for moral guidance, a growing number of people believe that the only ethic worth considering must rest on a biblical foundation. Is morality dependent upon God and "revealed (...) truths" found in scripture? Must this claim be accepted without question lest we risk the torment of eternal damnation for questioning it? Without critical evaluation and careful scrutiny, there is little hope of distinguishing truth from unfounded belief. How valuable is the Bible as a source for ethical truth? Do the scriptures truly have the insight needed to guide humankind safely through the moral dilemmas of modern society? What constitutes a biblical ethic? Should the Bible be construed as the only basis for moral teaching? Is it really the final authority on moral issues, or are there secular alternatives that can serve as guides to acceptable conduct within the human community? A distinguished group of social philosophers, biblical scholars, and ethicists met at the University of Richmond, Virginia, under the aegis of the Committee for the Scientific Examination of Religion and its Biblical Criticism Research Project, to address these and related questions. The essays in this provocative work demonstrate a diversity of perspective and breadth of insight that will shed much needed light on the nature of ethics. The contributors to this volume include: Robert S. Alley, Joe Edward Barnhart, Joseph L. Blau, Frank E. Eakin, Jr., Lewis S. Feuer, Joseph Fletcher, Theodor H. Gaster, James H. Hall, R. Joseph Hoffmann, Paul Kurtz, Gerald A. Larue, John Priest, Ellis Rivkin, Richard L. Rubenstein, and Richard Taylor. (shrink)

Many people are worried about the harmful effects of climate change but nevertheless enjoy some activities that contribute to the emission of greenhouse gas (driving, flying, eating meat, etc.), the main cause of climate change. How should such people make choices between engaging in and refraining from enjoyable greenhouse-gas-emitting activities? In this chapter, we look at the answer provided by decision theory. Some scholars think that the right answer is given by interactive decision theory, or game theory; and moreover think (...) that since private climate decisions are instances of the prisoner’s dilemma, one rationally should engage in these activities provided that one enjoys them. Others think that the right answer is given by expected utility theory, the best-known version of individual decision theory under risk and uncertainty. In this chapter, we review these different answers, with a special focus on the latter answer and the debate it has generated. (shrink)

Multidrug resistance resulting from expression of an energy‐dependent drug efflux pump encoded by the human MDR1 gene is a major impediment to effective cancer therapy. Pharmacologic intervention aimed at inhibiting this multidrug transporter should improve existing chemotherapy of human cancer, but drug development has been delayed by the difficulty and expense of developing valid animal models. Using recombinant DNA technology, a transgenic mouse has been engineered whose bone marrow is protected from the toxic effects of chemotherapy by expression of the (...) MDR1 gene. This animal system allows the rapid screening of drugs which inhibit the multidrug transporter and heralds a new era of using transgenic animals for pharmacologic screening. (shrink)

The Psalter exhibits a complex literary structure that not only determines its shape but also provides the reader with interpretive clues for reading both the whole and its parts.

Introduction, by G. Holton.--Three eighteenth-century social philosophers: scientific influences on their thought, by H. Guerlac.--Science and the human comedy: Voltaire, by H. Brown.--The seventeenth-century legacy: our mirror of being, by G. de Santillana.--Contemporary science and the contemporary world view, by P. Frank.--The growth of science and the structure of culture, by R. Oppenheimer.--The Freudian conception of man and the continuity of nature, by J. S. Bruner.--Quo vadis, by P. W. Bridgman.--Prospects for a new synthesis: science and the humanities as complementary (...) activities, by C. Morris.--A humanist looks at science, by H. M. Jones. (shrink)

Whether indeterminism undermines moral responsibility by subverting one or more of responsibility’s requirements is something that has received close attention in the recent literature on free will. In this paper, I take issue with Gerald Harrison’s attempt to deflect various considerations for the view that indeterminism threatens responsibility either by threatening the control that responsibility requires or by posing a problem of luck.

Gewirth and hare claim amoralism is contrary to reason. Gewirth believes amoralism to be logically inconsistent. Hare believes amoralism to be imprudent and hence irrational. By defining the problem as one of amoralism rather than 'non'moralism, Gewirth and hare assume illegitimate moral presuppositions. I show their arguments fail by comparing their arguments to the arguments given by someone who accepts the language and presuppositions of magic. I suggest that what is wrong with amoralism is that it leads to immoralism. If (...) this is so, Morality ultimately must be based upon basic moral insights or intuitions. (shrink)